Amaranth HDL (previously known as nMigen)
A modern hardware definition language and toolchain based on Python
migen
A Python toolbox for building complex digital hardware
MyHDL
Python as a hardware description and verification language
nMigen
A refreshed Python toolbox for building complex digital hardware
PipelineC
Open source C-like hardware description language with high-level-synthesis-like automatic pipelining and several other real life design inspired features.
pyFPGA
A Python package to use FPGA development tools programmatically
pyVHDLModel
An abstract language model of VHDL written in Python